INTELENCE®: An important option

INTELENCE® is a prescription medicine that is used to treat human immunodeficiency virus-1 (HIV-1) infection in combination with other HIV-1 medicines, in adults and children 2 years of age and older who have taken HIV-1 medicines in the past. HIV-1 is the virus that causes AIDS (Acquired Immune Deficiency Syndrome). INTELENCE® is not recommended for use in children less than 2 years of age.

How to take INTELENCE®

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Patient Information

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INTELENCE® (etravirine) Dosing Information

How should I take INTELENCE®?

  • Stay under the care of your healthcare provider during treatment with INTELENCE®.
  • Take INTELENCE® tablets every day exactly as prescribed by your healthcare provider.
  • Your healthcare provider will tell you how many INTELENCE® tablets to take and when to take them. Talk to your healthcare provider if you have questions about when to take INTELENCE®.
  • Take INTELENCE® 2 times each day.
  • If your child takes INTELENCE®, your healthcare provider will prescribe the right dose based on your child’s weight.
  • Always take INTELENCE® following a meal. Do not take INTELENCE® on an empty stomach. INTELENCE® may not work as well if you take it on an empty stomach.
  • Do not change your dose or stop taking INTELENCE® without first talking with your healthcare provider.
  • Swallow INTELENCE® tablets whole, with liquid, such as water. Do not chew the tablet(s).
  • It is important that you do not miss or skip doses of INTELENCE® during treatment.
  • When your supply of INTELENCE® starts to run low, get more from your healthcare provider or pharmacy. It is important not to run out of INTELENCE®. The amount of HIV in your blood may increase if the medicine is stopped even for a short time.
  • If you take too much INTELENCE®, call your healthcare provider or go to the nearest emergency room right away.

Recommended Dosage in Adult Patients
The recommended oral dosage of INTELENCE® for adult patients is 200 mg (one 200 mg tablet or two 100 mg tablets) taken twice daily following a meal. The type of food does not affect the exposure to INTELENCE®.

Recommended Dosage During Pregnancy
The recommended oral dosage of INTELENCE® for pregnant individuals is 200 mg (one 200 mg tablet or two 100 mg tablets) taken twice daily following a meal.

Recommended Dosage in Pediatric Patients (2 Years to Less Than 18 Years of Age)
The recommended dosage of INTELENCE® for pediatric patients 2 years to less than 18 years of age and weighing at least 10 kg is based on body weight (see Table 1 in the Prescribing Information) not exceeding the recommended adult dosage. INTELENCE® should be taken orally, following a meal. The type of food does not affect the exposure to INTELENCE®.

Janssen CarePath Care Coordinator
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For patients unable to swallow the INTELENCE® tablets whole:

INTELENCE® can be taken another way–in water

If you are unable to swallow INTELENCE® tablets whole, you may take your dose of INTELENCE® as follows:


Step
1

Measure approximately 5 mL (1 teaspoon) of water and pour into a cup.


Step
2

Place the tablets in the cup containing 5 mL of water. If needed, add more water to cover the tablets. Do not put the tablets in other liquids.


Step
3

Stir well until the water looks milky.


Step
4

Add a small amount (approximately 15 mL or 1 tablespoon) of liquid. Water may be used, but adding orange juice or milk rather than water may improve taste. Do not use warm (temperature more than 104°F or 40°C) or carbonated beverages.


Step
5

Drink the mixture right away.


Step
6

Add more orange juice, milk, or water to the cup to rinse the cup several times and completely swallow each time to make sure you take your entire dose of INTELENCE®.


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